иммунотерапия онкология лимфосистема

Virus fiber Е7 is capable to break regulation of the control клеточого a cycle, forming a stable inactive complex with a series of fibers regulating a cellular cycle; stimulates succession of events in a S-phase of a cellular cycle by инициации репликации virus genes and infringement of regulation пролиферации the transformed cells{cages}. The opportunity of uncontrollable synthesis cellular ДНК under influence of fiber Е7 is supposed. Thus, fiber Е7 is multifunctional due to interaction with cellular fibers; fiber Е7 is capable to cancel a stop of cells{cages} in a G1-phase of a cellular cycle, to render митогенное influence and to stimulate uncontrollable synthesis ДНК [12,13,16,22]. Подробнее...

The sizes of tumoral formations{educations} after циторедуктивной operations essentially influence results of the subsequent therapy and the forecast of the patient. So, average life expectancy of patients with the sizes of residual tumoral units less than 0,5 sm make 40 months, and at the sizes of 18 and 6 months of 0,5-2 and more 2 sm accordingly [2]. For this reason optimum executed циторедуктивной operation considers at what the maximal sizes of the staying tumoral formations{educations} do not exceed 2 see. In some centers under optimum циторедукцией accept the sizes of the staying tumoral formations{educations} less than 1 see. For achievement similar циторедукции the surgeon sometimes should carry out plural resections of a gut, a liver, a spleen, a bladder, a diaphragm, to use ultrasonic аспиратор and laser коагулятор for removal{distance} fine диссеминатов. Clearly, that циторедуктивные operations are considered technically complex{difficult} and demand high qualification of the surgeon specializing in онкогинекологии. Despite of all this, frequency of performance optimum циторедукции in conducting{leading} clinics of the world makes 23-54 %, and only separate authors achieve it at 75-90 % of patients. Подробнее...