научный центр онкологии рамн москва

In spite of the fact that анастрозол has shown the superiority before тамоксифеном, last while remains the standard адъювантной гормонотерапии (term of reception - 5 years) as time of supervision in research АТАС, equal 33 months, is, in opinion of the majority of the experts, insufficient to recommend анастрозол as the standard адъювантной эндокринотерапии. Подробнее...

Originally in researches GOG 111 and OV-10 it has been shown, that паклитаксел in a combination with цисплатином essentially improve results of treatment in comparison with a combination цисплатин-циклофосфан. High нейротоксичность combinations цисплатин-паклитаксел has made actual replacement цисплатина on карбоплатин. In several researches [Neijt J.P., AGO, GOG-158] it has been shown, that such replacement does not result in deterioration of the remote results and essentially improves bearableness of treatment. Then in research GOG-132 it is revealed, that at purpose{assignment} as combinations паклитаксела and цисплатина, and consecutive use of two preparations (цисплатина for the first line and паклитаксела for the second line), life expectancy of patients is identical. Thus, necessity of use таксанов at various stages of treatment for achievement of the best results has been once again underlined. Подробнее...