онкология в гинекологии лечение
The concept of virus nature РШМ has a long history and is inextricably related with researches кондилом various localizations. Генитальные кондиломы are described even in works on antique medicine. The first assumptions of the infectious nature of a cancer шейки a uterus has stated in 1842 Rigoni-Stern. In 1903 Borrel and Bosc have offered the virus theory of development of tumours; Rous, Kidd (1938); Rous, Friedewald (1941) have received proofs of amplification{strengthening} of activity опухолеродных viruses at the presence of cancerogenic substances. Achievements in эксперементальной to virology have allowed L.A.Zilberu (1945), later Horsfall (1963) and Southam (1964) to formulate positions about опухолеродных viruses as the agents transforming a normal cell{cage} in tumoral by means of influence on its{her} genetic material, action of these agents differs from infectious, and in the further duplication of already arisen tumoral cells{cages} опухолеродные viruses of a role do not play. Подробнее...
In research AGO-GINECO authors have estimated expediency of addition антрациклинов to a combination карбоплатин паклитаксел. Inclusion эпирубицина has strengthened toxicity of a combination, but has not improved results of therapy [10]. In research SCOTROC comparison available today in our disposal таксанов is made: паклитаксела and доцетаксела [11]. Both preparations in a combination with карбоплатином have shown identical frequency of objective effects and time before progressing. The combination карбоплатин-паклитаксел possessed more expressed нейротоксичностью while карбоплатин-доцетаксел caused development нейтропении is more often. Подробнее...