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Thus, gene Е6 is multifunctional fiber, трансактивирующая which activity assumes participation in regulation of a transcription, interaction with a gene р53, his{its} degradation, in infringement of the mechanism of the control of cellular growth and process of a differentiation of cells{cages}. However till now there is no harmonous representation about the mechanism of interaction of virus fiber Е6 with cellular fibers in vivo. Virus fiber Е7 cooperates with cellular fiber Rb105, Rb-related fibers and Н1-киназой. These interactions are the independent processes necessary for effective transformation of cells{cages} by fiber. Fiber pRb (р105) is a product of a gene ретинобластомы, супрессора cellular growth. Подробнее...

Results of one of the most representative on number of participants (9366 patients with an operable cancer dairy железы in менопаузе) researches АТАС in which comparison of efficiency тамоксифена (20 mg / day is lead{carried out}), анастрозола (1 mg / day) and are submitted to their combination at адъювантном application within 5 years. Подробнее...