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The received results testify to statistically significant advantage of mode ТАС in increase безрецидивной and the general{common} survival rate, is especial in subgroups of patients with positive РЭ and РП, and also at involving in process 1-3 axillary лимфоузлов (tab. 1). At the same time, use of mode ТАС was accompanied by the greater гематологической toxicity and the septic complications connected to it{her}, the truth in one group is not marked the lethal outcomes caused by a sepsis. Подробнее...

Virus fiber Е7 is capable to break regulation of the control клеточого a cycle, forming a stable inactive complex with a series of fibers regulating a cellular cycle; stimulates succession of events in a S-phase of a cellular cycle by инициации репликации virus genes and infringement of regulation пролиферации the transformed cells{cages}. The opportunity of uncontrollable synthesis cellular ДНК under influence of fiber Е7 is supposed. Thus, fiber Е7 is multifunctional due to interaction with cellular fibers; fiber Е7 is capable to cancel a stop of cells{cages} in a G1-phase of a cellular cycle, to render митогенное influence and to stimulate uncontrollable synthesis ДНК [12,13,16,22]. Подробнее...