рак вульвы

Efficiency hypodermic мастэктомии at a distance dairy железы called a fabric into question Goldman and Goldwyn in 1973 when, after executed on standard technics{technical equipment} hypodermic мастэктомии, the residual fabric has been found in 83 % [24]. Other research which has been lead{which has been carried out} to 1991 Barton et al. [25], in which was compared the quantity{amount} of the fabric left after modified radical мастэктомии and full ferruterous мастэктомии by a plenty интрооперационных биопсий, result had 5 % positive биопсий at both types of operations, at average quantity{amount} of a left fabric dairy железы 0,2 % from initial volume. The conclusion which has been made, consist that full ferruterous мастэктомия is effective procedure for removal{distance} of a fabric dairy железы in comparison with modified radical мастэктомией. Подробнее...

For the first time serious assumptions of a possible{probable} role of viruses of papillomas in development РШМ have been stated in the middle of 70th years. It is necessary to emphasize, that definition of concept " a virus as этиологический the factor of development of a tumour " is based on a combination of the following criteria: 1) regular detection in tumoral cells{cages} virus ДНК (both in integrated, and in эписомальной to the form); 2) клонированные virus genes in cellular systems in vitro should induce malignant transformation of cells{cages}, including cells{cages} of the person; 3) regular экспрессия virus genes in tumoral cells{cages}; 4) existence in the nature of the similar viruses, capable to induce formation{education} of tumours at эксперементальных animals; 5) the epidemiological data confirming communication{connection} between tumoral process and presence of a virus genetic material in tumoral cells{cages}. The technique of molecular cloning has allowed to create a physical card{map} of viruses with the help эндонуклеаз, to define{determine} a site and sequence of the proteins coded by a virus [13,19.] has been shown, that in cells{cages} РШМ by a gene of a virus is actively transcribed, and crucial importance for development РШМ has персистенция virus генома [23]. The cellular lines received from a tumoral fabric шейки of a uterus, allow to carry out{spend} the comparative analysis of lines and tumours on персистенцию virus ДНК, function and экспрессию genes ДНК of a virus of a papilloma of person (ВПЧ). In fabrics эпителиальных дисплазий and карцином шейки a uterus during tumoral transformation regulation of a transcription virus онкогенов is broken, that is shown by quantitative distinctions in экспрессии early genes Е6 and Е7, playing the basic role in an induction of malignant growth of cells{cages} [22]. Подробнее...