онкология рак опухоль

Process of integration is accompanied by partial loss of a genetic material of a virus, thus virus a gene irrespective of делеций loses ability to full репликации, and in the cells{cages} containing integrated cellular gene, there is no production of virus particles. Assume, that integration represents активационный the mechanism of a progression неоплазии from дисплазии a heavy degree to a cancer; she{it} originally carries поликлональный character. Most frequently in канцерогенез шейки a uterus are involved certain{determined} speed up chromosomes 5,6,10,11 and 17. Integration virus ДНК induces instability cellular генома and as consequence{investigation} an induction of infringements in the various chromosomes tested on loss of heterozygosity. The site of primary integration virus ДНК is not determined, quite often it{he} settles down near to cellular онкогенов [4]. Подробнее...

Malignant tumours - tumor malignum, grow much faster. Environments have no. Tumoral cells{cages} and тяжи them will penetrate into surrounding fabrics (инфильтративный growth), damaging{injuring} them. Sprouting lymphatic or a blood vessel, they can be transferred by a current of blood or a lymph to lymph nodes or the remote body and to form there the secondary center of tumoral growth - a metastasis. The histologic picture of a malignant tumour considerably differs from a fabric from which she{it} has developed. Its{her} cells{cages} атипичны, полиморфны, with a plenty митозов. A characteristic attribute of a tumoral fabric is анаплазия - return to more primitive type. Морфологически it is shown by loss of a differentiation, is functional - loss of specific function. Подробнее...