спектрометрия в онкологии

At patients РШМ earlier beginning of a sexual life is marked in comparison with control groups. Often change of sexual partners, early age of the first sorts [2,5,17] have adverse value. In a number of epidemiological and клинико-statistical researches decrease{reduction} in desease РШМ at women has been marked, whose husbands were exposed циркумцизии. This fact connected with possible{probable} cancerogenic action смегмы. Other authors have come out with the assumption of carcinogenicity contained in sperm гистона and протамина, capable in culture of a fabric to cause атипию multilayered flat эпителия шейки a uterus [3,4]. A number{line} of authors specify also some increase in desease инвазивным РШМ at women with a low social and economic level and the educational qualification [2,17], in other works such correlation is absent [3,14]. The factor of a heredity, significant at a cancer эндометря and яичников, at РШМ special does not play a role [2,3,8,14]. Till now the question on a role of the trauma connected to sorts and abortions, and contraceptive means as the moments contributing to development of tumours шейки of a uterus is discussed. Подробнее...

Middle age of patients has made 64 years; 84 % had positive рецепторный the status, 34 % - positive axillary лимфоузлы, 21 % of patients received адъювантную chemotherapy earlier. Reception анастрозола associated with reduction of risk рецидивирования on 17 % (1 % in absolute values) in comparison with тамоксифеном (р=0,0129); the combination анастрозола and тамоксифена did not differ on efficiency from monotherapy тамоксифеном. It is necessary to note, that reception анастрозола associated also with essential decrease{reduction} in risk of development контралатерального a cancer dairy железы (р=0,0068). Костно-muscular pains, and also crises of bones much more often were observed in group анастрозола while тромбоэмболические episodes and gynecologic complications, including a cancer эндометрия, much more often met in group тамоксифена. Thus, анастрозол it can be considered{examined} as alternative тамоксифену at patients in менопаузе with positive receptors. Reception анастрозола has considerably lowered frequency of development контралатерального a cancer, and this fact is the basis for studying group ингибиторов ароматазы as means of preventive maintenance of a cancer dairy железы in groups with the raised{increased} risk. Подробнее...