химия онкология грудь

For acknowledgement{confirmation} of some positions it is necessary to continue molecular and цитогенетические researches on all tumours аногенитальной the zones, connected with ВПЧ. Now, after accumulation of a plenty epidemiological and эксперементальных the data, РШМ it is represented by unique model for studying virus канцерогенеза and definitions of associations between молекулярно-genetic changes caused by a virus and features of clinical current and the forecast of disease. Подробнее...

Thus, gene Е6 is multifunctional fiber, трансактивирующая which activity assumes participation in regulation of a transcription, interaction with a gene р53, his{its} degradation, in infringement of the mechanism of the control of cellular growth and process of a differentiation of cells{cages}. However till now there is no harmonous representation about the mechanism of interaction of virus fiber Е6 with cellular fibers in vivo. Virus fiber Е7 cooperates with cellular fiber Rb105, Rb-related fibers and Н1-киназой. These interactions are the independent processes necessary for effective transformation of cells{cages} by fiber. Fiber pRb (р105) is a product of a gene ретинобластомы, супрессора cellular growth. Подробнее...