периферический рак

Unresolved there is a question on optimum duration of chemotherapy of the first line. Today it is possible to recommend an individual approach in each concrete case. At a stage of chemotherapy of the first line it is necessary to aspire to achievement of full regress with disappearance of all displays of illness including normalization of level СА-125, and then to fix the achieved effect carrying out of 2-3 more additional rates. At achievement of partial regress it is necessary to continue chemotherapy till the moment when during two last rates stabilization of illness is marked, estimating on the sizes of residual tumoral weights and concentration of tumoral markers. By own experience I can tell, that in these cases at the majority of patients the number of courses of treatment will make from 6 up to 12, but not less than 6. In case of stabilization of illness it is necessary to limit volume of treatment by 6 rates after which end therapy can be stopped up to attributes of progressing or it is continued with use of modes of the second line depending on the general{common} condition of the patient and its{her} attitude{relation} to the further carrying out chemotherapy. At progressing illness it is necessary to pass to modes of the second line of chemotherapy. Подробнее...

The data on influence of long steroid contraception on frequency дисплазии and a cancer шейки a uterus разноречивы. Insignificant increase in frequency дисплазии and преинвазивного РШМ at the women using steroid contraceptives, have noted Andolsek with соавт. (1983), Piper (1985.) Svan and Brown (1981), Vassey with соавт. (1983) have defined{determined} relative risk РШМ equal 1,5 and 2,5 accordingly, in other researches it is not marked correlations between application of hormonal contraceptives and РШМ [3]. Experts the CART (Geneva, 1985) Came to a conclusion, that the treatment of the data on use of steroid contraceptives is inconvenient as because of the big number of preparations and absence of the authentic cytologic control over a condition эпителия шейки a uterus prior to the beginning and during application of steroid contraceptives, and owing to interrelation of frequency of application of contraceptives and sexual activity. Now there are convincing data on raised{increased} risk РШМ at smoking щенщин. Hellberg with соавт. (1983), Greenberg with соавт. (1986), Winkelstein (1985), Brinton (1986) mark association of smoking with the early beginning of a sexual life and often change of sexual partners, Hoffman with соавт. (1985), Sasson with соавт. (1985) suppose to a - cancerogenic role contained in a tobacco smoke of nicotine and котинина [4]. Подробнее...