диагностика рака груди

In research AGO-GINECO authors have estimated expediency of addition антрациклинов to a combination карбоплатин паклитаксел. Inclusion эпирубицина has strengthened toxicity of a combination, but has not improved results of therapy [10]. In research SCOTROC comparison available today in our disposal таксанов is made: паклитаксела and доцетаксела [11]. Both preparations in a combination with карбоплатином have shown identical frequency of objective effects and time before progressing. The combination карбоплатин-паклитаксел possessed more expressed нейротоксичностью while карбоплатин-доцетаксел caused development нейтропении is more often. Подробнее...

At patients with resistant (an interval less than 6 months) or рефрактерными to цисплатину tumours яичника for carrying out of chemotherapy it is necessary to choose the preparations which were earlier not used at a stage of an induction. Derivative platinums are not appointed this patient. In this case frequency of objective effect does not exceed 20-25 % at average life expectancy of 6-10 months. Подробнее...