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Authors conclude that the percent{interest} of development of local relapses does not differ from the data рецидивирования the ambassador стандарной мастэктомии, however these data force to think of influence of local relapses on the general{common} survival rate at the given category of patients. In this connection the approach to treatment of relapses should be same, as well as at relapses after modified radical мастэктомии. Подробнее...

Originally in researches GOG 111 and OV-10 it has been shown, that паклитаксел in a combination with цисплатином essentially improve results of treatment in comparison with a combination цисплатин-циклофосфан. High нейротоксичность combinations цисплатин-паклитаксел has made actual replacement цисплатина on карбоплатин. In several researches [Neijt J.P., AGO, GOG-158] it has been shown, that such replacement does not result in deterioration of the remote results and essentially improves bearableness of treatment. Then in research GOG-132 it is revealed, that at purpose{assignment} as combinations паклитаксела and цисплатина, and consecutive use of two preparations (цисплатина for the first line and паклитаксела for the second line), life expectancy of patients is identical. Thus, necessity of use таксанов at various stages of treatment for achievement of the best results has been once again underlined. Подробнее...