мутации генов онкология

The data of the first intermediate analysis of results of research BCRIG01 are published, in which comparison of efficiency of standard mode FAC (500/50/500) with a таксан-containing mode (with inclusion Таксотера) ТАС (75/50/500 (1) is lead{carried out}. Both modes were used with an interval of 3 weeks in quantity{amount} of 6 rates. This first published research estimating a role доцетаксела (Таксотера) in адъювантной of therapy of a cancer dairy железы. Earlier in two other researches (С9344 and В30) the role паклитаксела has been investigated, and one of them (С9344) has shown increase безрецидивной and the general{common} survival rate at patients with рецептороотрицательными tumours at use паклитаксела is consecutive with a mode the EXPERT. Подробнее...

The data on influence of long steroid contraception on frequency дисплазии and a cancer шейки a uterus разноречивы. Insignificant increase in frequency дисплазии and преинвазивного РШМ at the women using steroid contraceptives, have noted Andolsek with соавт. (1983), Piper (1985.) Svan and Brown (1981), Vassey with соавт. (1983) have defined{determined} relative risk РШМ equal 1,5 and 2,5 accordingly, in other researches it is not marked correlations between application of hormonal contraceptives and РШМ [3]. Experts the CART (Geneva, 1985) Came to a conclusion, that the treatment of the data on use of steroid contraceptives is inconvenient as because of the big number of preparations and absence of the authentic cytologic control over a condition эпителия шейки a uterus prior to the beginning and during application of steroid contraceptives, and owing to interrelation of frequency of application of contraceptives and sexual activity. Now there are convincing data on raised{increased} risk РШМ at smoking щенщин. Hellberg with соавт. (1983), Greenberg with соавт. (1986), Winkelstein (1985), Brinton (1986) mark association of smoking with the early beginning of a sexual life and often change of sexual partners, Hoffman with соавт. (1985), Sasson with соавт. (1985) suppose to a - cancerogenic role contained in a tobacco smoke of nicotine and котинина [4]. Подробнее...