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The opportunity of interrelation неоплазий шейки a uterus with venereal diseases was for many years discussed. In group of the women suffering инвазивным РШМ, higher frequency of revealing of nonspecific microflora is marked, switching трихомонадные and гарднерелловы infections [3,6]. Examples of such influence were discussed in attitude{relation} Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, a virus of a simple herpes of type 2, a cytomegalovirus, a virus of a papilloma of the person [3,19]. Epidemiological researches have convincingly shown, that a conclusive risk factor of occurrence of precancer changes and a cancer шейки a uterus is генитальная папилломавирусная the infection, accompanying папилломавирусной infections of sexual ways influence at early stages of development неоплазий and do not influence on already arisen РШМ [5,13,14,23]. Подробнее...

Middle age of patients has made 64 years; 84 % had positive рецепторный the status, 34 % - positive axillary лимфоузлы, 21 % of patients received адъювантную chemotherapy earlier. Reception анастрозола associated with reduction of risk рецидивирования on 17 % (1 % in absolute values) in comparison with тамоксифеном (р=0,0129); the combination анастрозола and тамоксифена did not differ on efficiency from monotherapy тамоксифеном. It is necessary to note, that reception анастрозола associated also with essential decrease{reduction} in risk of development контралатерального a cancer dairy железы (р=0,0068). Костно-muscular pains, and also crises of bones much more often were observed in group анастрозола while тромбоэмболические episodes and gynecologic complications, including a cancer эндометрия, much more often met in group тамоксифена. Thus, анастрозол it can be considered{examined} as alternative тамоксифену at patients in менопаузе with positive receptors. Reception анастрозола has considerably lowered frequency of development контралатерального a cancer, and this fact is the basis for studying group ингибиторов ароматазы as means of preventive maintenance of a cancer dairy железы in groups with the raised{increased} risk. Подробнее...