ранняя диагностика рака

To this time concern definition Melnick (1952), A.D.Timofeevskim (1961) with the help of электронно-microscopic technics{technical equipment} of constant presence вирусоподобных телец in папиллломах. Barrett (1954) has established the fact of transfer генитальных кондилом at гетеросексуальных the sexual relations, Dunn and Ogilvie (1968) have allocated virus particles from генитальных warts [4,9]. As the characteristic of cytologic changes in эпителии шейки a uterus, observable at папилломатозе, Aure (1949) described перинуклеарные changes in cells{cages} at research мазков with шейки a uterus. For the description of similar changes Koss, Durfee (1956) have entered into clinical practice the term " койлоцитотическая атипия " for which large cells{cages} with rather small гиперхромным a nucleus surrounded with transparent cytoplasm are characteristic. Authors for the first time have noted communication{connection} between койлоцитотической атипией. дисплазией and РШМ. Woodruff, Peterson (1958) and Pitkin, Kent (1963) have described histologic characteristics of classical forms папилломатозных кондилом; long time папилломатозные кондиломы were considered as unique morphological display папилломавирусной infections of sexual ways [9,10]. Подробнее...

The arsenal of the antineoplastic means used for carrying out of chemotherapy of the second line is extraordinary great. To them concern паклитаксел, доцетаксел, топотекан, липосомальный доксорубицин, пероральный этопозид, винорельбин, гемцитабин, оксалиплатин, алтретамин, ифосфамид. So big list of preparations is more likely the certificate of that any of them does not allow to reach{achieve} long remissions at the majority of patients. Efficiency of them changes from 12 up to 40 % at average life expectancy of 9-12 months. Подробнее...