гиперотермия при лечении онкологии

The second purpose of operative treatment of the widespread cancer яичников is removal{distance} or the maximal resection as primariest tumour, and all its{her} metastasises. Removal{distance} of a great bulk of a tumour improves the general{common} condition of patients due to reduction of an intoxication and normalization of function of intestines. Besides циторедукция raises efficiency of the subsequent chemotherapy due to reduction of number of tumoral cells{cages} including resistant to chemotherapy, transition of the most part of the staying cells{cages} from a phase of rest in a phase of division, and removal{distance} it is bad васкуляризованных sites of a tumour in which hit of antineoplastic preparations is complicated. Подробнее...

The decision on a choice of preparations for chemotherapy of the second line should be based, first of all, on definition of sensitivity of a tumour to derivatives of platinum after chemotherapy of the first line. The interval between the termination{ending} of therapy of the first line and progressing of disease more than 6 months testifies to high sensitivity of a tumour derivatives of platinum. Such patient for treatment of relapses should be appointed a combination of derivatives of platinum and new preparations from among that are used for carrying out of the second line of chemotherapy. At separate patients with duration of remission more than 12 months probably carrying out of chemotherapy of the second line by the same combination which was used at a stage of an induction. Frequency of objective effect at use of a combination of derivatives of platinum (is $more often карбоплатина in view of his{its} smaller toxicity) and new preparations makes 30-50 % at average life expectancy of sick 12-14 months. Подробнее...