онкология в московской области

Modern молекулярно-trouble-shooting tests quickly move ahead in a direction of increase of their sensitivity and specificity. Now for identification virus ДНК various techniques of hybridization ДНК and molecular cloning are used. The most sensitive method now recognizes полимеразная chain reaction with типоспецифическими and species-specific праймерами, allowing to reveal virus sequences in геноме cells{cages} of tumours шейки a uterus in 95-100 % of cases [5,14,18,22]. Now it is identified more than 100 types ВПЧ, are in detail described more than 70 types, the fact is fixed, that certain types ВПЧ can infect strictly certain kind эпителия and to cause characteristic changes. Revealing of multi-variant approach of genotypes ВПЧ and identification of the data specific accumulation about malignant transformation генитальных кондилом have allowed to consider{examine} папилломавирус as possible{probable} этиологический the factor of development РШМ [13,15,20,23]. Подробнее...

Virus ДНК it is capable персистировать in a cell{cage} in эписомальной or the integrated forms. In fabrics эпителиальных дисплазий шейки a uterus are found out эписомальные forms ДНК ВПЧ. In most cases РШМ and in the cellular lines received from РШМ and containing ВПЧ, virus sequences are defined{determined} in the integrated form [21]. Подробнее...