нии онкологии в москве

The authentic establishment of association папилломавирусов with development генитальной неоплазии has allowed to approach closely to an opportunity to analyze complex{difficult} and questions at issue of correlation caused ВПЧ молекулярно-genetic changes with clinical features and forecast РШМ. Clinical current РШМ is influenced with histologic type and a degree of a differentiation of a tumour, the size of a primary tumour, depth инвазии subject fabrics and involving in tumoral process прилежащих to шейке a uterus of fabrics, лимфососудистого spaces and регионарных лимфоузлов. Forecast РШМ the big sizes of a primary tumour, a low degree of a differentiation of a tumour, presence of metastatic defeat регионарных лимфоузлов worsen, young age of patients [2,14]. Messages, соотносящие молекулярно-genetic determinants of the ВПЧ-INFECTION at РШМ with гистопатологическими both clinical features of tumours and forecast РШМ, contain inconsistent results. ВПЧ type 16 meets in высокодифференцированных плоскоклеточных tumours while ВПЧ type 18 it is associated with плоскоклеточными tumours of a low degree of a differentiation and аденокарциномами [13,14] is more often. Подробнее...

Considering these data, in the beginning of 90th the first publications published by several surgeons which concerned changes of traditional cuts{sections} at modified radical мастэктомии with the purpose of improvement of results of one-stage reconstruction dairy железы have appeared. In particular, the first work on this theme has been published in magazine " Plastic and Reconstructive Surgery " in 1990 Toth et al. in section " Ideas and innovations " [28]. In this work the case of one-stage reconstruction of both dairy желез concerning a mucous cancer right dairy железы at the patient with risk of development of a cancer in another dairy iron has been submitted. In connection with that at the patient dairy железы were sizable in a combination with expressed птозом, it has been executed modified radical мастэктомия with cuts{sections} on type редукционной plastics and preventive мастэктомия at the left with one-stage reconstruction билатеральным completely деэпителизированным cross-section ректо-абдоминальным (TРAM) a rag c good aesthetic result. In one year, the same group of surgeons publishes the report on 17 patients with which one-stage reconstruction c has been executed by application of a similar technique which the author has named " Wise pattern " with use of various techniques of reconstruction. In this work the term " мастэктомия with preservation of a leather{skin} " for the first time has sounded, and also principles of performance of similar operative interventions have been sounded. These principles included: 1) Removal{Distance} of all fabric dairy железы 2) removal{distance} сосково-ареолярного a complex 3) removal{distance} of a leather{skin} in a projection preoperative биопсии 4) an opportunity to execute axillary лимфаденэктомию from the same access. Подробнее...