онкология ргму

Virus ДНК it is capable персистировать in a cell{cage} in эписомальной or the integrated forms. In fabrics эпителиальных дисплазий шейки a uterus are found out эписомальные forms ДНК ВПЧ. In most cases РШМ and in the cellular lines received from РШМ and containing ВПЧ, virus sequences are defined{determined} in the integrated form [21]. Подробнее...

From all identified types of viruses of papillomas 34 are associated with defeat аногенитальной areas. Viruses of papillomas infect базальные layers эпителия (the most "vulnerable" site the zone of transition multilayered flat эпителия in cylindrical эпителий is). Caused патоморфологические changes Kurz (1993) and Schiffman (1994) are classified by viruses as: 1) good-quality атипия; 2) LSIL (Low-grade Squamous Intraepithelial Lesions) or CIN-I (Cervical Intraepithelial Neoplasia) - дисплазия an easy degree without койлоцитоза or with attributes койлоцитоза; 3) HSIL (High-grade Squamous Intraepithelial Lesions), CIN-II-moderate дисплазия; 4) expressed дисплазия or интраэпителиальный a cancer (in situ) - CIN-III. Discussion concerning classification дисплазии and преинвазивного РШМ till now proceeds. In the domestic literature it is accepted to allocate three degrees of weight дисплазии эпителия шейки a uterus, интраэпителиальный РШМ it is allocated into separate group [10]. The group дисплазий эпителия шейки a uterus is heterogeneous both with патоморфологической, and from the virologic point of view. Now there is no confidence, that various degrees дисплазий are stages канцерогенеза [18]. Подробнее...