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Process of integration is accompanied by partial loss of a genetic material of a virus, thus virus a gene irrespective of делеций loses ability to full репликации, and in the cells{cages} containing integrated cellular gene, there is no production of virus particles. Assume, that integration represents активационный the mechanism of a progression неоплазии from дисплазии a heavy degree to a cancer; she{it} originally carries поликлональный character. Most frequently in канцерогенез шейки a uterus are involved certain{determined} speed up chromosomes 5,6,10,11 and 17. Integration virus ДНК induces instability cellular генома and as consequence{investigation} an induction of infringements in the various chromosomes tested on loss of heterozygosity. The site of primary integration virus ДНК is not determined, quite often it{he} settles down near to cellular онкогенов [4]. Подробнее...

Modern techniques of reconstruction dairy железы after radical мастэктомии, be this use силиконовых имплантатов or moving of кожно-muscular rags, forms and volume dairy железы collide{face} with a challenge of formation anew. Despite of significant progress in the field of the reconstructive - plastic surgery, the plenty of techniques connected to development, this problem, and also a problem appreciable рубцов after reconstruction create necessity for the further perfection of approaches to reconstruction dairy железы the ambassador мастэктомии. Подробнее...