рак молочной железы гормонотерапия

In the first reviews the data on wide circulation ВПЧ in a population and his{its} expressed онкогенном potential [20] are submitted. Authors pay attention, that only инфицирования a virus of a papilloma it is not enough of one for an induction of tumoral growth, and specify a role кофакторов in ВПЧ-DEPENDENT канцерогенезе. Thus, ифекция a virus of a papilloma is necessary, but not a determinative of development of malignant process, иммортализации and transformations are involved in processes the cellular factors participating in regulation of a cellular cycle and a differentiation of cells{cages} [5,20,22]. Подробнее...

The concept of virus nature РШМ has a long history and is inextricably related with researches кондилом various localizations. Генитальные кондиломы are described even in works on antique medicine. The first assumptions of the infectious nature of a cancer шейки a uterus has stated in 1842 Rigoni-Stern. In 1903 Borrel and Bosc have offered the virus theory of development of tumours; Rous, Kidd (1938); Rous, Friedewald (1941) have received proofs of amplification{strengthening} of activity опухолеродных viruses at the presence of cancerogenic substances. Achievements in эксперементальной to virology have allowed L.A.Zilberu (1945), later Horsfall (1963) and Southam (1964) to formulate positions about опухолеродных viruses as the agents transforming a normal cell{cage} in tumoral by means of influence on its{her} genetic material, action of these agents differs from infectious, and in the further duplication of already arisen tumoral cells{cages} опухолеродные viruses of a role do not play. Подробнее...