диагностика рака кости
The question of preservation of a leather{skin} dairy железы with the purpose of improvement of results of reconstruction remains unresolved from the beginning of XX century. Variants of operations at which removal{distance} of a fabric dairy железы with preservation of a leather{skin} and сосково-ареолярного a complex was carried out with the purpose of the prevention{warning} of development of a cancer in opposite iron and one-stage reconstruction, have started to be developed since 1917 when Bartlett has executed the first hypodermic мастэктомию with one-stage replacement of the removed fabric dairy железы a free fatty fabric [12.] Rice and Strickler in 1951 publish the data on results hypodermic мастэктомии concerning good-quality diseases [13]. Also in this problem actively are engaged Freeman [14, 15] which uses эндопротезы for reconstruction dairy железы, Pennisi and Capozzi [16-18] and Woods [19]. All these surgeons carry out the same operation at which rather thick skin rags will be mobilized, and also the disk of a fabric dairy железы under сосково-ареолярным a complex for improvement of his{its} blood supply is left. The general{common} name of this operation - hypodermic мастэктомия. Подробнее...
Process of integration is accompanied by partial loss of a genetic material of a virus, thus virus a gene irrespective of делеций loses ability to full репликации, and in the cells{cages} containing integrated cellular gene, there is no production of virus particles. Assume, that integration represents активационный the mechanism of a progression неоплазии from дисплазии a heavy degree to a cancer; she{it} originally carries поликлональный character. Most frequently in канцерогенез шейки a uterus are involved certain{determined} speed up chromosomes 5,6,10,11 and 17. Integration virus ДНК induces instability cellular генома and as consequence{investigation} an induction of infringements in the various chromosomes tested on loss of heterozygosity. The site of primary integration virus ДНК is not determined, quite often it{he} settles down near to cellular онкогенов [4]. Подробнее...
