лечение стволовыми клетками в онкологии
The data on influence of long steroid contraception on frequency дисплазии and a cancer шейки a uterus разноречивы. Insignificant increase in frequency дисплазии and преинвазивного РШМ at the women using steroid contraceptives, have noted Andolsek with соавт. (1983), Piper (1985.) Svan and Brown (1981), Vassey with соавт. (1983) have defined{determined} relative risk РШМ equal 1,5 and 2,5 accordingly, in other researches it is not marked correlations between application of hormonal contraceptives and РШМ [3]. Experts the CART (Geneva, 1985) Came to a conclusion, that the treatment of the data on use of steroid contraceptives is inconvenient as because of the big number of preparations and absence of the authentic cytologic control over a condition эпителия шейки a uterus prior to the beginning and during application of steroid contraceptives, and owing to interrelation of frequency of application of contraceptives and sexual activity. Now there are convincing data on raised{increased} risk РШМ at smoking щенщин. Hellberg with соавт. (1983), Greenberg with соавт. (1986), Winkelstein (1985), Brinton (1986) mark association of smoking with the early beginning of a sexual life and often change of sexual partners, Hoffman with соавт. (1985), Sasson with соавт. (1985) suppose to a - cancerogenic role contained in a tobacco smoke of nicotine and котинина [4]. Подробнее...
The concept of virus nature РШМ has a long history and is inextricably related with researches кондилом various localizations. Генитальные кондиломы are described even in works on antique medicine. The first assumptions of the infectious nature of a cancer шейки a uterus has stated in 1842 Rigoni-Stern. In 1903 Borrel and Bosc have offered the virus theory of development of tumours; Rous, Kidd (1938); Rous, Friedewald (1941) have received proofs of amplification{strengthening} of activity опухолеродных viruses at the presence of cancerogenic substances. Achievements in эксперементальной to virology have allowed L.A.Zilberu (1945), later Horsfall (1963) and Southam (1964) to formulate positions about опухолеродных viruses as the agents transforming a normal cell{cage} in tumoral by means of influence on its{her} genetic material, action of these agents differs from infectious, and in the further duplication of already arisen tumoral cells{cages} опухолеродные viruses of a role do not play. Подробнее...
