онкология мочевого пузыря

Considering these data, in the beginning of 90th the first publications published by several surgeons which concerned changes of traditional cuts{sections} at modified radical мастэктомии with the purpose of improvement of results of one-stage reconstruction dairy железы have appeared. In particular, the first work on this theme has been published in magazine " Plastic and Reconstructive Surgery " in 1990 Toth et al. in section " Ideas and innovations " [28]. In this work the case of one-stage reconstruction of both dairy желез concerning a mucous cancer right dairy железы at the patient with risk of development of a cancer in another dairy iron has been submitted. In connection with that at the patient dairy железы were sizable in a combination with expressed птозом, it has been executed modified radical мастэктомия with cuts{sections} on type редукционной plastics and preventive мастэктомия at the left with one-stage reconstruction билатеральным completely деэпителизированным cross-section ректо-абдоминальным (TРAM) a rag c good aesthetic result. In one year, the same group of surgeons publishes the report on 17 patients with which one-stage reconstruction c has been executed by application of a similar technique which the author has named " Wise pattern " with use of various techniques of reconstruction. In this work the term " мастэктомия with preservation of a leather{skin} " for the first time has sounded, and also principles of performance of similar operative interventions have been sounded. These principles included: 1) Removal{Distance} of all fabric dairy железы 2) removal{distance} сосково-ареолярного a complex 3) removal{distance} of a leather{skin} in a projection preoperative биопсии 4) an opportunity to execute axillary лимфаденэктомию from the same access. Подробнее...

During tumoral transformation the key role is played with virus genes Е6 and Е7 which activity is supervised регуляторным by site URR. This site генома contains area of the virus promotor, a locus репликации, энхенсерные elements, активирующие the sequences necessary for репликации virus ДНК, sites of linkage for fiber Е2, cellular factors of a transcription, receptors of a progesterone and глюкокортикоидных hormones [16]. In регуляторной areas генома the promotor р97 (ВПЧ type 16), р105 (ВПЧ type 18), regulating экспрессию virus genes settles down; activity of the promotor is adjusted by virus and cellular fibers. Онкобелок Е6 plays a role коактиватора, cooperating with factors of a transcription and elements of the basic транскрипционного a complex. Подробнее...