онкология карцинома яичника
The first researches devoted эпидемиологии РШМ, have appeared in a century. Rigoni-Stern in 1842 has published the data based on studying of the register of death in Verona with 1760 on 1830. It{he} has noticed, that РШМ much more often caused death of married women and widows and did not meet at virgins and монахинь. This circumstance has allowed the scientist to state a hypothesis about infectious origin РШМ. Known interest submit data, published F.Gagnon (1950), - at studying 13000 case records монахинь Montreal and Quebec РШМ has not been found out never. The author connected similar results with low frequency of inflammatory diseases шейки a uterus at монахинь. In review Mogaji (1973) it is shown, that гистологически confirmed плоскоклеточный РШМ at virgins represents an exclusive rarity, these data are confirmed with researches Kessler (1976) and Skoqg (1982). Results of the epidemiological researches concerning a role in occurrence РШМ of the early beginning of a sexual life, early first pregnancy, often change of sexual partners, and also the infectious diseases transmitted in the sexual way are published. Подробнее...
To this time concern definition Melnick (1952), A.D.Timofeevskim (1961) with the help of электронно-microscopic technics{technical equipment} of constant presence вирусоподобных телец in папиллломах. Barrett (1954) has established the fact of transfer генитальных кондилом at гетеросексуальных the sexual relations, Dunn and Ogilvie (1968) have allocated virus particles from генитальных warts [4,9]. As the characteristic of cytologic changes in эпителии шейки a uterus, observable at папилломатозе, Aure (1949) described перинуклеарные changes in cells{cages} at research мазков with шейки a uterus. For the description of similar changes Koss, Durfee (1956) have entered into clinical practice the term " койлоцитотическая атипия " for which large cells{cages} with rather small гиперхромным a nucleus surrounded with transparent cytoplasm are characteristic. Authors for the first time have noted communication{connection} between койлоцитотической атипией. дисплазией and РШМ. Woodruff, Peterson (1958) and Pitkin, Kent (1963) have described histologic characteristics of classical forms папилломатозных кондилом; long time папилломатозные кондиломы were considered as unique morphological display папилломавирусной infections of sexual ways [9,10]. Подробнее...
