медицинские клиники по онкологии
In the first reviews the data on wide circulation ВПЧ in a population and his{its} expressed онкогенном potential [20] are submitted. Authors pay attention, that only инфицирования a virus of a papilloma it is not enough of one for an induction of tumoral growth, and specify a role кофакторов in ВПЧ-DEPENDENT канцерогенезе. Thus, ифекция a virus of a papilloma is necessary, but not a determinative of development of malignant process, иммортализации and transformations are involved in processes the cellular factors participating in regulation of a cellular cycle and a differentiation of cells{cages} [5,20,22]. Подробнее...
Middle age of patients has made 64 years; 84 % had positive рецепторный the status, 34 % - positive axillary лимфоузлы, 21 % of patients received адъювантную chemotherapy earlier. Reception анастрозола associated with reduction of risk рецидивирования on 17 % (1 % in absolute values) in comparison with тамоксифеном (р=0,0129); the combination анастрозола and тамоксифена did not differ on efficiency from monotherapy тамоксифеном. It is necessary to note, that reception анастрозола associated also with essential decrease{reduction} in risk of development контралатерального a cancer dairy железы (р=0,0068). Костно-muscular pains, and also crises of bones much more often were observed in group анастрозола while тромбоэмболические episodes and gynecologic complications, including a cancer эндометрия, much more often met in group тамоксифена. Thus, анастрозол it can be considered{examined} as alternative тамоксифену at patients in менопаузе with positive receptors. Reception анастрозола has considerably lowered frequency of development контралатерального a cancer, and this fact is the basis for studying group ингибиторов ароматазы as means of preventive maintenance of a cancer dairy железы in groups with the raised{increased} risk. Подробнее...