центральный институт онкологии

People have got used to search for external enemies. Will find scientists the reason of a cancer, we shall avoid her{it} also all will be in the order. Will fail. Desease a cancer is in direct dependence on age, is approximately doubled each five years. That is, in 60 years the risk to be ill a cancer more than in 10 times is higher, than in 40 years and more than in 50 times is higher, than in 20 years. And irrespective of external "cancerogenic" factors which though exist, but incommensurably smaller weight, than this, "spontaneous" desease connected to natural deterioration and breakages of an organism at a cellular level have it. Подробнее...

Thus, gene Е6 is multifunctional fiber, трансактивирующая which activity assumes participation in regulation of a transcription, interaction with a gene р53, his{its} degradation, in infringement of the mechanism of the control of cellular growth and process of a differentiation of cells{cages}. However till now there is no harmonous representation about the mechanism of interaction of virus fiber Е6 with cellular fibers in vivo. Virus fiber Е7 cooperates with cellular fiber Rb105, Rb-related fibers and Н1-киназой. These interactions are the independent processes necessary for effective transformation of cells{cages} by fiber. Fiber pRb (р105) is a product of a gene ретинобластомы, супрессора cellular growth. Подробнее...