лор онколог москва
The first researches devoted эпидемиологии РШМ, have appeared in a century. Rigoni-Stern in 1842 has published the data based on studying of the register of death in Verona with 1760 on 1830. It{he} has noticed, that РШМ much more often caused death of married women and widows and did not meet at virgins and монахинь. This circumstance has allowed the scientist to state a hypothesis about infectious origin РШМ. Known interest submit data, published F.Gagnon (1950), - at studying 13000 case records монахинь Montreal and Quebec РШМ has not been found out never. The author connected similar results with low frequency of inflammatory diseases шейки a uterus at монахинь. In review Mogaji (1973) it is shown, that гистологически confirmed плоскоклеточный РШМ at virgins represents an exclusive rarity, these data are confirmed with researches Kessler (1976) and Skoqg (1982). Results of the epidemiological researches concerning a role in occurrence РШМ of the early beginning of a sexual life, early first pregnancy, often change of sexual partners, and also the infectious diseases transmitted in the sexual way are published. Подробнее...
Thus, today in our disposal there is a lot of effective preparations and modes for treatment of patients by the widespread cancer яичников. As the first line of chemotherapy it is possible to use the combined modes (карбоплатин-паклитаксел, цисплатин-паклитаксел, карбоплатин-доцетаксел or CAP) or monotherapy by preparations of platinum (цисплатин 100 mg / m2 each 3 weeks of 6 rates or 50 mg / m2 weekly within 9 weeks, карбоплатин AUC x 5-7 each 3-4 weeks of 6 rates). The patients who have received at the first stage of treatment modes without inclusion таксанов, should receive necessarily таксаны in the second line of chemotherapy. At purpose{assignment} of the above-stated preparations and combinations in full dozes and recommended intervals it is possible to expect for reception of average time before progressing 15-17 months and average life expectancy of 30-36 months. Подробнее...