хпронический лейкоз

In 1997 the works devoted to an oncological estimation of the given approach in reconstructive - plastic surgery dairy железы began to appear. So Carlson in 1997 has published materials of research [34], where compared frequency of development of local relapses and postoperative complications in groups of patients by which have been executed standard radical мастэктомия (188 operations, the average period of supervision 48,2 мес) and мастэктомия to preservation of a leather{skin} (327, the average period of supervision 37,5 мес) with one-stage reconstruction dairy железы with 1989 on 1994. Local relapses инвазивного a cancer in group стандарных мастэктомий have made 9,5 %, and in group мастэктомии with preservation of a leather{skin} - 4,8 %. Interventions were not required from 45 % of patients in the first group on opposite dairy iron while in the second group at 65 % of patients satisfactory symmetry after the first operation has been achieved. Also the percent{interest} некроза skin rags after мастэктомии was compared. In the first group it{he} has made 11,2 %, and in group мастэктомии with preservation of a leather{skin} of 10,7 %, i.e. essentially did not differ. Unfortunately, authors do not explain, to what decrease{reduction} in number of relapses almost twice in group where the theoretical risk of development of relapse should be higher can be connected. Подробнее...

Unresolved there is a question on optimum duration of chemotherapy of the first line. Today it is possible to recommend an individual approach in each concrete case. At a stage of chemotherapy of the first line it is necessary to aspire to achievement of full regress with disappearance of all displays of illness including normalization of level СА-125, and then to fix the achieved effect carrying out of 2-3 more additional rates. At achievement of partial regress it is necessary to continue chemotherapy till the moment when during two last rates stabilization of illness is marked, estimating on the sizes of residual tumoral weights and concentration of tumoral markers. By own experience I can tell, that in these cases at the majority of patients the number of courses of treatment will make from 6 up to 12, but not less than 6. In case of stabilization of illness it is necessary to limit volume of treatment by 6 rates after which end therapy can be stopped up to attributes of progressing or it is continued with use of modes of the second line depending on the general{common} condition of the patient and its{her} attitude{relation} to the further carrying out chemotherapy. At progressing illness it is necessary to pass to modes of the second line of chemotherapy. Подробнее...