меланома и послеоперационное лечение

The decision on a choice of preparations for chemotherapy of the second line should be based, first of all, on definition of sensitivity of a tumour to derivatives of platinum after chemotherapy of the first line. The interval between the termination{ending} of therapy of the first line and progressing of disease more than 6 months testifies to high sensitivity of a tumour derivatives of platinum. Such patient for treatment of relapses should be appointed a combination of derivatives of platinum and new preparations from among that are used for carrying out of the second line of chemotherapy. At separate patients with duration of remission more than 12 months probably carrying out of chemotherapy of the second line by the same combination which was used at a stage of an induction. Frequency of objective effect at use of a combination of derivatives of platinum (is $more often карбоплатина in view of his{its} smaller toxicity) and new preparations makes 30-50 % at average life expectancy of sick 12-14 months. Подробнее...

1491 patient with a cancer has taken part in research BCRIG01 dairy железы with positive axillary лимфоузлами; middle age has made 49 years, 62 % of patients had from 1 up to 3 лимфоузлов, at 69 % of a tumour were рецепторопозитивными on РЭ and РП, at 20 % - positive on HER2/neu. All patients having positive РЭ and РП, received also тамоксифен in a doze of 20 mg / ЯТФ. Within 5 years. The median of time of supervision at the moment of the analysis of results has made 33 (0-49) months. Подробнее...