гистология при раке шейки матки
Thus, today in our disposal there is a lot of effective preparations and modes for treatment of patients by the widespread cancer яичников. As the first line of chemotherapy it is possible to use the combined modes (карбоплатин-паклитаксел, цисплатин-паклитаксел, карбоплатин-доцетаксел or CAP) or monotherapy by preparations of platinum (цисплатин 100 mg / m2 each 3 weeks of 6 rates or 50 mg / m2 weekly within 9 weeks, карбоплатин AUC x 5-7 each 3-4 weeks of 6 rates). The patients who have received at the first stage of treatment modes without inclusion таксанов, should receive necessarily таксаны in the second line of chemotherapy. At purpose{assignment} of the above-stated preparations and combinations in full dozes and recommended intervals it is possible to expect for reception of average time before progressing 15-17 months and average life expectancy of 30-36 months. Подробнее...
Break of a ring molecule virus ДНК can occur in any place, however most frequently - in area Е1/Е2; exception is area URR-Е6-Е7, which интактна as in морфологически not changed эпителии and at дисплазиях, and in tumoral cells{cages}. Disappearance супрессорной causes functions of virus fiber Е2 суперэкспрессию virus онкогенов Е6-Е7, трансформирующее which action promotes a progression неоплазий. It is supposed, that gene Е1 participates in suppression of the virus promotor, consequence{investigation} of a mutation of gene Е1 are activation of a transcription virus генома and increase трансформирующей activity virus онкогенов [16,23]. Подробнее...