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The data on influence of long steroid contraception on frequency дисплазии and a cancer шейки a uterus разноречивы. Insignificant increase in frequency дисплазии and преинвазивного РШМ at the women using steroid contraceptives, have noted Andolsek with соавт. (1983), Piper (1985.) Svan and Brown (1981), Vassey with соавт. (1983) have defined{determined} relative risk РШМ equal 1,5 and 2,5 accordingly, in other researches it is not marked correlations between application of hormonal contraceptives and РШМ [3]. Experts the CART (Geneva, 1985) Came to a conclusion, that the treatment of the data on use of steroid contraceptives is inconvenient as because of the big number of preparations and absence of the authentic cytologic control over a condition эпителия шейки a uterus prior to the beginning and during application of steroid contraceptives, and owing to interrelation of frequency of application of contraceptives and sexual activity. Now there are convincing data on raised{increased} risk РШМ at smoking щенщин. Hellberg with соавт. (1983), Greenberg with соавт. (1986), Winkelstein (1985), Brinton (1986) mark association of smoking with the early beginning of a sexual life and often change of sexual partners, Hoffman with соавт. (1985), Sasson with соавт. (1985) suppose to a - cancerogenic role contained in a tobacco smoke of nicotine and котинина [4]. Подробнее...

Considering these data, in the beginning of 90th the first publications published by several surgeons which concerned changes of traditional cuts{sections} at modified radical мастэктомии with the purpose of improvement of results of one-stage reconstruction dairy железы have appeared. In particular, the first work on this theme has been published in magazine " Plastic and Reconstructive Surgery " in 1990 Toth et al. in section " Ideas and innovations " [28]. In this work the case of one-stage reconstruction of both dairy желез concerning a mucous cancer right dairy железы at the patient with risk of development of a cancer in another dairy iron has been submitted. In connection with that at the patient dairy железы were sizable in a combination with expressed птозом, it has been executed modified radical мастэктомия with cuts{sections} on type редукционной plastics and preventive мастэктомия at the left with one-stage reconstruction билатеральным completely деэпителизированным cross-section ректо-абдоминальным (TРAM) a rag c good aesthetic result. In one year, the same group of surgeons publishes the report on 17 patients with which one-stage reconstruction c has been executed by application of a similar technique which the author has named " Wise pattern " with use of various techniques of reconstruction. In this work the term " мастэктомия with preservation of a leather{skin} " for the first time has sounded, and also principles of performance of similar operative interventions have been sounded. These principles included: 1) Removal{Distance} of all fabric dairy железы 2) removal{distance} сосково-ареолярного a complex 3) removal{distance} of a leather{skin} in a projection preoperative биопсии 4) an opportunity to execute axillary лимфаденэктомию from the same access. Подробнее...