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At patients with resistant (an interval less than 6 months) or рефрактерными to цисплатину tumours яичника for carrying out of chemotherapy it is necessary to choose the preparations which were earlier not used at a stage of an induction. Derivative platinums are not appointed this patient. In this case frequency of objective effect does not exceed 20-25 % at average life expectancy of 6-10 months. Подробнее...

Virus fiber Е7 is capable to break regulation of the control клеточого a cycle, forming a stable inactive complex with a series of fibers regulating a cellular cycle; stimulates succession of events in a S-phase of a cellular cycle by инициации репликации virus genes and infringement of regulation пролиферации the transformed cells{cages}. The opportunity of uncontrollable synthesis cellular ДНК under influence of fiber Е7 is supposed. Thus, fiber Е7 is multifunctional due to interaction with cellular fibers; fiber Е7 is capable to cancel a stop of cells{cages} in a G1-phase of a cellular cycle, to render митогенное influence and to stimulate uncontrollable synthesis ДНК [12,13,16,22]. Подробнее...