онкология эффективное лечение
During tumoral transformation the key role is played with virus genes Е6 and Е7 which activity is supervised регуляторным by site URR. This site генома contains area of the virus promotor, a locus репликации, энхенсерные elements, активирующие the sequences necessary for репликации virus ДНК, sites of linkage for fiber Е2, cellular factors of a transcription, receptors of a progesterone and глюкокортикоидных hormones [16]. In регуляторной areas генома the promotor р97 (ВПЧ type 16), р105 (ВПЧ type 18), regulating экспрессию virus genes settles down; activity of the promotor is adjusted by virus and cellular fibers. Онкобелок Е6 plays a role коактиватора, cooperating with factors of a transcription and elements of the basic транскрипционного a complex. Подробнее...
The cancer dairy железы now is most frequently meeting malignant новообразованием among women, with annually increasing parameters of desease [1]. Despite of the big popularity органосохраняющего treatments, his{its} application is limited to early stages of a cancer dairy железы with a tumour no more than 3 sm, absence clinically positive axillary лимфоузлов, the size dairy железы, localization of a tumour and a number{line} of other reasons [2]. The increase in number of local relapses and quite often unsatisfactory aesthetic results [3] also takes place. Also frequency of application органосохраняющего treatments depends on quality of diagnostics of early stages of disease in concrete medical institution. Therefore the basic type of radical intervention at a cancer dairy железы still is modified radical мастэктомия in updatings Маддена and a plenty of the patients who have transferred this operative мешательство, experience the significant psychological difficulties connected to loss dairy железы [4]. Подробнее...