онкология метастаза

Process of integration is accompanied by partial loss of a genetic material of a virus, thus virus a gene irrespective of делеций loses ability to full репликации, and in the cells{cages} containing integrated cellular gene, there is no production of virus particles. Assume, that integration represents активационный the mechanism of a progression неоплазии from дисплазии a heavy degree to a cancer; she{it} originally carries поликлональный character. Most frequently in канцерогенез шейки a uterus are involved certain{determined} speed up chromosomes 5,6,10,11 and 17. Integration virus ДНК induces instability cellular генома and as consequence{investigation} an induction of infringements in the various chromosomes tested on loss of heterozygosity. The site of primary integration virus ДНК is not determined, quite often it{he} settles down near to cellular онкогенов [4]. Подробнее...

It is possible to offer two explanations of this phenomenon. First, quality of performance циторедуктивных operations therefore the sizes of residual formations{educations} and volume of residual tumoral weight after performance of operative intervention were essentially reduced has improved. The second reason is connected with the advent of the new antineoplastic preparations possessing activity at a cancer яичников. To such preparations concern, in particular, таксаны (паклитаксел and доцетаксел). Подробнее...