скенирование костей скелета при онкологии

There are messages on detection virus ДНК in cells{cages} РШМ both in integrated, and in эписомальной forms. Essential distinctions in character of integration ВПЧ of types 16 and 18 come to light. On the basis of the data on forms of integration virus ДНК assumptions of the possible{probable} importance of both forms персистенции ДНК ВПЧ types 16 and 18 are stated, and integration is not a determining part in the mechanism of an induction туморогенеза [23]. Подробнее...

Process of integration is accompanied by partial loss of a genetic material of a virus, thus virus a gene irrespective of делеций loses ability to full репликации, and in the cells{cages} containing integrated cellular gene, there is no production of virus particles. Assume, that integration represents активационный the mechanism of a progression неоплазии from дисплазии a heavy degree to a cancer; she{it} originally carries поликлональный character. Most frequently in канцерогенез шейки a uterus are involved certain{determined} speed up chromosomes 5,6,10,11 and 17. Integration virus ДНК induces instability cellular генома and as consequence{investigation} an induction of infringements in the various chromosomes tested on loss of heterozygosity. The site of primary integration virus ДНК is not determined, quite often it{he} settles down near to cellular онкогенов [4]. Подробнее...