онкология рак горла
Инфицированность ВПЧ type 18 contacts the worse forecast Walker (1989) and Burnett (1992), Riou (1990) and Higgins (1991) specify higher parameters of death rate in case of ВПЧ-NEGATIVE tumours, in researches Hоweey (1991), Sebbelov (1991), Chen (1993), Ikenberg (1994) similar law has not been revealed [цит. On 14]. However results of similar researches are put under doubt by the modern data on revealing sequences virus генома a method полимеразной chain reaction in 95-100 % of cases плоскоклеточного a cancer and аденокарцином шейки a uterus [18,23]. The age of patients, on one data, is not connected to молекулярно-genetic determinants of infection ВПЧ while other authors specify, that ВПЧ type 18 or ВПЧ type 16 come to light at younger patients is more often. Stage FIGO, by results of one researches, has not been connected to молекулярно-genetic determinants of infection ВПЧ [14,18]. Подробнее...
From all identified types of viruses of papillomas 34 are associated with defeat аногенитальной areas. Viruses of papillomas infect базальные layers эпителия (the most "vulnerable" site the zone of transition multilayered flat эпителия in cylindrical эпителий is). Caused патоморфологические changes Kurz (1993) and Schiffman (1994) are classified by viruses as: 1) good-quality атипия; 2) LSIL (Low-grade Squamous Intraepithelial Lesions) or CIN-I (Cervical Intraepithelial Neoplasia) - дисплазия an easy degree without койлоцитоза or with attributes койлоцитоза; 3) HSIL (High-grade Squamous Intraepithelial Lesions), CIN-II-moderate дисплазия; 4) expressed дисплазия or интраэпителиальный a cancer (in situ) - CIN-III. Discussion concerning classification дисплазии and преинвазивного РШМ till now proceeds. In the domestic literature it is accepted to allocate three degrees of weight дисплазии эпителия шейки a uterus, интраэпителиальный РШМ it is allocated into separate group [10]. The group дисплазий эпителия шейки a uterus is heterogeneous both with патоморфологической, and from the virologic point of view. Now there is no confidence, that various degrees дисплазий are stages канцерогенеза [18]. Подробнее...
