онкология мезотелиома

It is possible to offer two explanations of this phenomenon. First, quality of performance циторедуктивных operations therefore the sizes of residual formations{educations} and volume of residual tumoral weight after performance of operative intervention were essentially reduced has improved. The second reason is connected with the advent of the new antineoplastic preparations possessing activity at a cancer яичников. To such preparations concern, in particular, таксаны (паклитаксел and доцетаксел). Подробнее...

During tumoral transformation the key role is played with virus genes Е6 and Е7 which activity is supervised регуляторным by site URR. This site генома contains area of the virus promotor, a locus репликации, энхенсерные elements, активирующие the sequences necessary for репликации virus ДНК, sites of linkage for fiber Е2, cellular factors of a transcription, receptors of a progesterone and глюкокортикоидных hormones [16]. In регуляторной areas генома the promotor р97 (ВПЧ type 16), р105 (ВПЧ type 18), regulating экспрессию virus genes settles down; activity of the promotor is adjusted by virus and cellular fibers. Онкобелок Е6 plays a role коактиватора, cooperating with factors of a transcription and elements of the basic транскрипционного a complex. Подробнее...