лапораскопия детский онкология

During many years was considered, that usual, flat (ювенильные) and генитальные warts are caused by one type папилломавируса, and distinctions in clinical current are caused by distinctions in localization. Sights at a pathology кондилом шейки a uterus have been considerably reconsidered after Meisels, Fortin (1976), Purola, Savia (1976) have described генитальные flat and inverted (эндофитные) кондиломы, having defined{determined} their basic difference from кондилом other localizations, and postulated цитоморфологические attributes папилломавирусной infections: коилоцитоз or баллонирование the cells{cages}, described increased, гиперхромными the nucleus surrounded with a precise zone of light cytoplasm. Later with the help электронно-microscopic, иммуногистохимических and ДНК-гибридизационных researches it has been confirmed them папилломавирусная этиология [9,20]. Подробнее...

The decision on a choice of preparations for chemotherapy of the second line should be based, first of all, on definition of sensitivity of a tumour to derivatives of platinum after chemotherapy of the first line. The interval between the termination{ending} of therapy of the first line and progressing of disease more than 6 months testifies to high sensitivity of a tumour derivatives of platinum. Such patient for treatment of relapses should be appointed a combination of derivatives of platinum and new preparations from among that are used for carrying out of the second line of chemotherapy. At separate patients with duration of remission more than 12 months probably carrying out of chemotherapy of the second line by the same combination which was used at a stage of an induction. Frequency of objective effect at use of a combination of derivatives of platinum (is $more often карбоплатина in view of his{its} smaller toxicity) and new preparations makes 30-50 % at average life expectancy of sick 12-14 months. Подробнее...