московский институт онкологии

Efficiency hypodermic мастэктомии at a distance dairy железы called a fabric into question Goldman and Goldwyn in 1973 when, after executed on standard technics{technical equipment} hypodermic мастэктомии, the residual fabric has been found in 83 % [24]. Other research which has been lead{which has been carried out} to 1991 Barton et al. [25], in which was compared the quantity{amount} of the fabric left after modified radical мастэктомии and full ferruterous мастэктомии by a plenty интрооперационных биопсий, result had 5 % positive биопсий at both types of operations, at average quantity{amount} of a left fabric dairy железы 0,2 % from initial volume. The conclusion which has been made, consist that full ferruterous мастэктомия is effective procedure for removal{distance} of a fabric dairy железы in comparison with modified radical мастэктомией. Подробнее...

During tumoral transformation the key role is played with virus genes Е6 and Е7 which activity is supervised регуляторным by site URR. This site генома contains area of the virus promotor, a locus репликации, энхенсерные elements, активирующие the sequences necessary for репликации virus ДНК, sites of linkage for fiber Е2, cellular factors of a transcription, receptors of a progesterone and глюкокортикоидных hormones [16]. In регуляторной areas генома the promotor р97 (ВПЧ type 16), р105 (ВПЧ type 18), regulating экспрессию virus genes settles down; activity of the promotor is adjusted by virus and cellular fibers. Онкобелок Е6 plays a role коактиватора, cooperating with factors of a transcription and elements of the basic транскрипционного a complex. Подробнее...