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лейкоз илечение

The opportunity of interrelation неоплазий шейки a uterus with venereal diseases was for many years discussed. In group of the women suffering инвазивным РШМ, higher frequency of revealing of nonspecific microflora is marked, switching трихомонадные and гарднерелловы infections [3,6]. Examples of such influence were discussed in attitude{relation} Treponema pallidum, Neisseria gonorrhoeae, Chlamydia trachomatis, a virus of a simple herpes of type 2, a cytomegalovirus, a virus of a papilloma of the person [3,19]. Epidemiological researches have convincingly shown, that a conclusive risk factor of occurrence of precancer changes and a cancer шейки a uterus is генитальная папилломавирусная the infection, accompanying папилломавирусной infections of sexual ways influence at early stages of development неоплазий and do not influence on already arisen РШМ [5,13,14,23]. Подробнее...

The authentic establishment of association папилломавирусов with development генитальной неоплазии has allowed to approach closely to an opportunity to analyze complex{difficult} and questions at issue of correlation caused ВПЧ молекулярно-genetic changes with clinical features and forecast РШМ. Clinical current РШМ is influenced with histologic type and a degree of a differentiation of a tumour, the size of a primary tumour, depth инвазии subject fabrics and involving in tumoral process прилежащих to шейке a uterus of fabrics, лимфососудистого spaces and регионарных лимфоузлов. Forecast РШМ the big sizes of a primary tumour, a low degree of a differentiation of a tumour, presence of metastatic defeat регионарных лимфоузлов worsen, young age of patients [2,14]. Messages, соотносящие молекулярно-genetic determinants of the ВПЧ-INFECTION at РШМ with гистопатологическими both clinical features of tumours and forecast РШМ, contain inconsistent results. ВПЧ type 16 meets in высокодифференцированных плоскоклеточных tumours while ВПЧ type 18 it is associated with плоскоклеточными tumours of a low degree of a differentiation and аденокарциномами [13,14] is more often. Подробнее...