острый лимфобластный лейкоз

The authentic establishment of association папилломавирусов with development генитальной неоплазии has allowed to approach closely to an opportunity to analyze complex{difficult} and questions at issue of correlation caused ВПЧ молекулярно-genetic changes with clinical features and forecast РШМ. Clinical current РШМ is influenced with histologic type and a degree of a differentiation of a tumour, the size of a primary tumour, depth инвазии subject fabrics and involving in tumoral process прилежащих to шейке a uterus of fabrics, лимфососудистого spaces and регионарных лимфоузлов. Forecast РШМ the big sizes of a primary tumour, a low degree of a differentiation of a tumour, presence of metastatic defeat регионарных лимфоузлов worsen, young age of patients [2,14]. Messages, соотносящие молекулярно-genetic determinants of the ВПЧ-INFECTION at РШМ with гистопатологическими both clinical features of tumours and forecast РШМ, contain inconsistent results. ВПЧ type 16 meets in высокодифференцированных плоскоклеточных tumours while ВПЧ type 18 it is associated with плоскоклеточными tumours of a low degree of a differentiation and аденокарциномами [13,14] is more often. Подробнее...

Braverman with соавт. (5) have estimated a hormonal background at 16 women (middle age 43 years) with come{stepped} owing to chemotherapy аменореей in from 3 till 44 months (a median - 8,5 months). The level сывороточного эстрадиола at 60 % of patients corresponded{met} пременопаузальному in spite of the fact that the level фолликулостимулирующего hormone (ФСГ) was in постменопаузальном a range. The received data are necessary for considering at purpose{assignment} ингибиторов ароматазы to women with induced chemotherapy аменореей. It is obvious, that at this category of patients менопаузальный it is necessary to confirm the status definition of a level эстрадиола and ФСГ which further should be supervised each 3 months. Подробнее...