лечение рака молочной железы

At patients РШМ earlier beginning of a sexual life is marked in comparison with control groups. Often change of sexual partners, early age of the first sorts [2,5,17] have adverse value. In a number of epidemiological and клинико-statistical researches decrease{reduction} in desease РШМ at women has been marked, whose husbands were exposed циркумцизии. This fact connected with possible{probable} cancerogenic action смегмы. Other authors have come out with the assumption of carcinogenicity contained in sperm гистона and протамина, capable in culture of a fabric to cause атипию multilayered flat эпителия шейки a uterus [3,4]. A number{line} of authors specify also some increase in desease инвазивным РШМ at women with a low social and economic level and the educational qualification [2,17], in other works such correlation is absent [3,14]. The factor of a heredity, significant at a cancer эндометря and яичников, at РШМ special does not play a role [2,3,8,14]. Till now the question on a role of the trauma connected to sorts and abortions, and contraceptive means as the moments contributing to development of tumours шейки of a uterus is discussed. Подробнее...

The decision on a choice of preparations for chemotherapy of the second line should be based, first of all, on definition of sensitivity of a tumour to derivatives of platinum after chemotherapy of the first line. The interval between the termination{ending} of therapy of the first line and progressing of disease more than 6 months testifies to high sensitivity of a tumour derivatives of platinum. Such patient for treatment of relapses should be appointed a combination of derivatives of platinum and new preparations from among that are used for carrying out of the second line of chemotherapy. At separate patients with duration of remission more than 12 months probably carrying out of chemotherapy of the second line by the same combination which was used at a stage of an induction. Frequency of objective effect at use of a combination of derivatives of platinum (is $more often карбоплатина in view of his{its} smaller toxicity) and new preparations makes 30-50 % at average life expectancy of sick 12-14 months. Подробнее...