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From all identified types of viruses of papillomas 34 are associated with defeat аногенитальной areas. Viruses of papillomas infect базальные layers эпителия (the most "vulnerable" site the zone of transition multilayered flat эпителия in cylindrical эпителий is). Caused патоморфологические changes Kurz (1993) and Schiffman (1994) are classified by viruses as: 1) good-quality атипия; 2) LSIL (Low-grade Squamous Intraepithelial Lesions) or CIN-I (Cervical Intraepithelial Neoplasia) - дисплазия an easy degree without койлоцитоза or with attributes койлоцитоза; 3) HSIL (High-grade Squamous Intraepithelial Lesions), CIN-II-moderate дисплазия; 4) expressed дисплазия or интраэпителиальный a cancer (in situ) - CIN-III. Discussion concerning classification дисплазии and преинвазивного РШМ till now proceeds. In the domestic literature it is accepted to allocate three degrees of weight дисплазии эпителия шейки a uterus, интраэпителиальный РШМ it is allocated into separate group [10]. The group дисплазий эпителия шейки a uterus is heterogeneous both with патоморфологической, and from the virologic point of view. Now there is no confidence, that various degrees дисплазий are stages канцерогенеза [18]. Подробнее...

In communication{connection} with obviously not radical character циторедуктивной to operation by all sick cancer яичника IC-IV stages show carrying out of chemotherapy. Last years there is an intensive search of the most effective combination for carrying out of the first line of chemotherapy. In table 2 results of the most important рандомизированных the researches published in the literature or reported in a preliminary kind at the international congresses and conferences are resulted. At the analysis of results of treatment the essential increase in life expectancy of patients with the widespread cancer яичников is evident. If in the end 80-Х--the beginning of 90th years average life expectancy made 18-24 months in the majority of the resulted researches this parameter has increased till 30-38 months. Подробнее...