нифхи онкология

The cellular lines received from tumours, and биоптаты from патологически the changed fabrics long time remained a unique material for studying mechanisms папилломавирусной infections. Unsuccessfulness of reproduction папилломавируса in culture of cells{cages}, absence convincing серологических tests for a virus infection, variety of displays цитопатических effects of a virus and subjectivity of an estimation and interpretation a virus - induced cytologic and гистопатологических changes constrained the further researches. Подробнее...

Viruses of papillomas concern to family паповавирусов (Papovaviridae) and represent group of the viruses amazing large horned livestock, birds and the person which are capable to infect базальные cells{cages} of a leather{skin} and flat эпителия. Папилломавирусы - one of the most heterogeneous groups of viruses which criterion of a differentiation is the degree of genetic relationship of viruses according to molecular hybridization: she{it} can change from 10 up to 85 %. Diameter of virus particles of 55 nanometers. The virus has no external environment. Капсид a virus will consist from 72 капсомеров. The detailed analysis of molecule ДНК ВПЧ became possible{probable} after development of a technique of splitting ДНК with use эндонуклеаз and the analysis of these fragments with the help gel - электрофореза. The given method has allowed to define{determine} characteristic pictures of splitting ДНК and to create a physical card{map} of an arrangement of points of splitting in геноме various папилломавирусов [20]. Подробнее...